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["宁夏医科大学2016年国家自然科学基金资助项目清单（64项）"]
["序号","项目批准号","负责人","项目名称","申请代码1","项目类别","批准金额","所在学院"]
[1,81602713,"王浩","抑制乳腺癌复发的DNA-蛋白质复合纳米颗粒治疗性疫苗的初步研究","H1611","青年科学基金项目",16,"基础医学院（16项）"]
[2,21665021,"姚惠琴","基于多重可控刺激响应型生物电催化构建生物分子逻辑门及其网络体系","B050202","地区科学基金项目",39]
[3,21667023,"朱美霖","宁夏北部农田重金属污染源解析及居民健康风险评估与时空预测研究","B070703",null,39]
[4,31660270,"丁娟","星形胶质细胞中ndrg2调控Aβ代谢在AD发生中的作用研究","C0901",null,38]
[5,31660336,"徐方","TNF-α介导的NF-κB 和Wnt通路正反馈调节促进LGR5+结肠干细胞恶变的分子机制","C0712",null,38]
[6,81660001,"梁锦屏","NOD信号对肺泡上皮细胞TLR介导抗结核分枝杆菌感染的免疫调节机制","H0104",null,38]
[7,81660047,"张鸣号","MAP1S调控TLRs信号通路介导同型半胱氨酸引起泡沫细胞自噬的分子机制","H0203",null,37]
[8,81660216,"文玉军","具有促血管神经再生功能的透明质酸复合载体携带嗅鞘细胞修复大鼠脊髓损伤的研究","H0910",null,36]
[9,81660258,"吴凯","滋养细胞凋亡中NSPcl沉默基因HOX转录调控模式的建立及表观遗传学调控机制","H0418",null,36]
[10,81660473,"孙建民","PI3 Kinase调控c-Kit突变的自活化及其致癌能力的研究","H1603",null,40]
[11,81660486,"高玉婧","Wnt5a在前列腺癌去势抵抗中的作用和机制研究","H1606",null,37]
[12,81660645,"姚遥","基于体液药理学和成分敲出-敲入策略的柴胡皂苷类成分治疗老年痴呆药效物质发现研究","H2803",null,37]
[56,81660136,"宋辉","MST1对诱导性多能干细胞分化成类β-细胞的作用及机制研究","H0704",null,35]
[13,81642001,"张建忠","2016年亚太神经再生论坛（APSNR2016）","H0912","应急管理项目",8]
[14,81670416,"姜怡邓","特异性lncRNA在同型半胱氨酸致动脉粥样硬化中表观遗传学机制研究","H0215","面上项目",60]
[15,81670798,"杨怡","丝氨酸/苏氨酸蛋白激酶Mst1通过细胞自噬途径调节非酒精性脂肪肝肝脏脂代谢的机制","H0719",null,48]
[16,81674096,"南一","基于TASCC回回甘松饮干预早期糖尿病肾病过程中肾小球固有细胞间跨越沟通的分子机制研究","H2720",null,62,"中医学院（3项）"]
[17,81660818,"高玉杰","基于固有大脑功能网络研究“龙虎交战”针法治疗偏头痛的机制","H2718","地区科学基金项目",33]
[18,81660829,"马科","基于PI3K/AKT及Notch信号通路回药爱康方对非小细胞肺癌作用机制的研究","H2720",null,42]
[19,31600744,"郭乐","靶向M细胞的乳酸菌表面展示投递体系LL-pSAM的构建及其在幽门螺旋杆菌多价表位疫苗中的实验研究","C080903","青年科学基金项目",20,"总医院（26项）"]
[20,81600853,"马坚","双生子样本全外显子组测序筛查非综合征型唇腭裂易感基因研究","H1403",null,18]
[21,31660030,"王振海","mTOR信号通路对布鲁氏菌侵染小胶质细胞自噬及极化的调控机制","C010603","地区科学基金项目",39]
[22,81660045,"何军","肌肉环指状蛋白2调控心肌线粒体蛋白质稳态的研究","H0203",null,37]
[23,81660056,"杨震","Ang1-7对心肌肥厚电生理重构的干预研究","H0205",null,37]
[24,81660060,"贾绍斌","高同型半胱氨酸血症激活巨噬细胞TRPV1促易损斑块形成机制研究","H0206",null,35]
[25,81660088,"张慧萍","lncRNA与miRNAs相互作用调控Rap1A在同型半胱氨酸致免疫炎症的机制研究","H0221",null,40]
[26,81660198,"马汉祥","Glu与GABA递质/受体系统介导椎管内麻醉的镇静作用及其机制研究","H0903",null,36]
[27,81660206,"刘萍","ERK1/2-Drp1分子通路在高血糖加重脑缺血损伤中的作用","H0906",null,36]
[28,81660221,"杨平","CLU 在阿尔茨海默病中介导 Tau 蛋白在神经元间转运的作用及机制","H0912",null,36]
[29,81660226,"王峰","岛叶皮质GABAB受体在匹罗卡品致痫大鼠再认记忆损害中的作用及机制研究","H0913",null,36]
[30,81660229,"倪新莉","Iduna调控Wnt通路在新生大鼠缺氧缺血性脑轴突损伤中的作用","H0914",null,36]
[31,81660251,"哈春芳","RAS/MEK/ERK通路介导NF-кB调节子宫内膜异位症细胞侵袭性的机制研究","H0406",null,37]
[32,81660257,"胡蓉","抗苗勒氏管激素通过cAMP/CREB调控子宫内膜蜕膜化的分子机制","H0417",null,37]
[33,81660290,"王琴","NLRP3炎症小体/caspase-1调控通路在肥胖心肌损伤中的作用及其机制研究","H1805",null,37]
[34,81660351,"魏军","群体感应调控基因abaR在鲍曼不动杆菌生物膜形成中的作用机制","H2002",null,37]
[35,81660370,"王自立","脊柱结核血清、尿液中特异循环miRNA标记物的筛选验证及其在成骨细胞分化中的调控机制研究","H0607",null,37]
[36,81660373,"金群华","Wnt/β-catenin信号通路对软骨和软骨下骨相互作用致骨关节炎发生、发展的调节机制研究","H0609",null,37]
[37,81660419,"夏鹤春","Per2基因调控p53信号通路促人脑胶质母细胞瘤干细胞凋亡的分子机制及放疗敏感性研究","H1618",null,37]
[38,81660500,"李涛","HDAC抑制剂通过STAT3/AKT/EMT信号轴抗三阴乳腺癌转移和复发的作用机制研究","H1609",null,37]
[39,81660505,"詹文华","PSCA介导左旋棉酚纳米粒子联合放射治疗诱导前列腺癌细胞凋亡与自噬的体内外生物学研究","H1610",null,35]
[40,81660506,"马伟","Akt3激活DNA-PKcs/DNA DSBs通路介导食管鳞癌的放疗抵抗","H1610",null,37]
[41,81660617,"张文萍","基于脑部OCT2特异性靶向的阿霉素转运脂质体的构建及其转运机制研究","H3110",null,40]
[42,81660690,"刘春莲","枸杞多糖改善早老性Immp2l突变小鼠生精功能及相关机制的研究","H2815",null,37]
[43,81660806,"李晓荣","基于PGC-1α-TFAM-ROS途径探讨六味地黄丸调控POF小鼠卵巢颗粒细胞线粒体功能的机制","H2711",null,40]
[44,81660530,"马万瑞","线粒体动态失衡介导的纳米银细胞毒性和亚硒酸钠的解毒作用","H2601",null,40]
[45,21666031,"王志忠","环糊精第一、二面羟基的选择性修饰及其结肠释药特性的研究","B060805","地区科学基金项目",40,"药学院（10项）"]
[46,81660254,"郑婕","基于PI3K/AKt信号通路探讨枸杞多糖改善糖尿病雄性大鼠生殖系统损伤的作用研究","H0411",null,36]
[47,81660261,"余建强","基于PI3K/Akt/GSK-3β信号通路研究氧化苦参碱抗新生儿脑缺血损伤的作用及机制","H0422",null,36]
[48,81660590,"刘艳华","肿瘤靶向共载前药胶束同步递送联合化疗药物协同抗肿瘤的研究","H3008",null,36.5]
[49,81660665,"王文苹","乳液法制备载药微球过程中的溶剂效应与调控机制","H2806",null,40]
[50,81660673,"李娟","基于DARTS技术的柴胡总皂苷治疗老年痴呆的CX3CR1相关作用机制研究","H2808",null,36]
[51,81660674,"周茹","基于IKK-IκB-NF-κB信号通路研究氧化槐果碱抗脑缺血损伤的作用及机制","H2808",null,37]
[52,81660700,"赵启鹏","回药木香油方抗脑缺血再灌注损伤的物质基础及对NLRP3信号网络的影响","H2818",null,36]
[53,21606137,"于永杰","樟树精油抗氧化关键成分确定、调控及协同机制研究","B060702","青年科学基金项目",20]
[54,81603227,"王汉卿","基于多维分析技术的甘草药材区域质量特征及生产区划研究","H2801",null,17]
[55,81602809,"何淑兰","NOS和Arg在克山病外周血单核细胞中对线粒体生物合成影响","H2401",null,17,"公共卫生与管理学院（5项）"]
[57,81660527,"徐海明","煤工尘肺患者体内乙酰胆碱酯酶活性的变化及其调控机制","H2402","地区科学基金项目",33]
[58,81660534,"王发选","LncRNA通过调控TGF-β1/Smad3信号通路在矽肺纤维化中的分子机制研究","H2602",null,41]
[59,81660537,"杨建军","基于PGC-1ɑ/Irisin/UCP1通路探讨枸杞多糖对非酒精脂肪肝肝细胞线粒体功能障碍的调控机制","H2603",null,40]
[60,81660565,"丁文清","学龄儿童青少年不同肥胖表型代谢组学及与血压关系的研究","H2610",null,34]
[61,81660385,"李胜玲","宁夏发展性照护理念的早产儿延续护理管理模式的构建研究","H1701",null,36,"护理与高职学院"]
[62,31660267,"刘昆梅","星形胶质细胞上调基因-1（AEG-1）通过调控星形胶质细胞活化影响癫痫发病的作用机制研究","C0901",null,38,"颅脑实验室"]
[63,81660212,"周翔鱼","不同髓鞘成分抗原诱导的小胶质细胞极化类型及其对少突胶质细胞系分化、衰老和凋亡的作用机制研究","H0907",null,36,"宁夏医科大学附属石嘴山市第一人民医院 "]
[64,81660813,"马会明","月见草油靶向FOXO1基因改善PCOS胰岛素抵抗的作用机制","H2717",null,38,"生育力实验室"]

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